Turkish Journal of Nephrology
Original Article

Ultrafi ltration is not Superior than Diuretics in Type 4 Cardiorenal Sydrome

1.

Bülent Ecevit University Faculty of Medicine, Department of Nephrology, Zonguldak, Turkey

2.

Dışkapı Yıldırım Beyazıt Education and Research Hospital, Clinic of Nephrology, Ankara, Turkey

3.

İstanbul Education and Research Hospital, Clinic of Nephrology, İstanbul, Turkey

4.

Atatürk State Hospital, Clinic of Nephrology, Zonguldak, Turkey

5.

Bülent Ecevit University Faculty of Medicine, Department of Cardiology, Zonguldak, Turkey

6.

Ege University Faculty of Medicine, Department of Internal Medicine, İzmir, Turkey

Turkish J Nephrol 2014; 23: 20-25
DOI: 10.5262/tndt.2014.1001.05
Read: 696 Downloads: 445 Published: 07 February 2019

OBJECTIVE: Cardiorenal syndrome (CRS) describes a dysregulation of the heart and kidneys affecting each other. Recently hemodialysis treatments were used more frequently. Aim was to analyze the effects of conventional diuretic and UF treatments.

MATERIAL and METHODS: Thirty-four Type 4 CRS diagnosed patients were included. Baseline characteristics were recorded. Echocardiography measured at the admission and at the end of the treatment.

RESULTS: The mean age 67.4±9.3 (51-93) years and follow-up period were 15.9±11.5 months. The patients were grouped as diuretic group, n=12 and UF group, n=22. At the beginning mitral valve A wave, blood urea nitrogen and creatinine values were higher in the UF group while creatinine values were higher in the UF group compared to diuretic group at the end of the study. Although basal ejection fraction (EF) values were not different, it was higher in the UF group at the end of the study (42.38±12.70 % and 29±3.67 %, p <0.05). During follow-up mortality rates were not different in both groups (diuretic group, 6 patients (17.6 %), the UF group 1 patient (2.9 %), (p> 0.05).

CONCLUSION: In Type 4 CRS, mortality and hospital admissions were not reduced by UF treatment but cardiac function assessed by EF was signifi cantly improved suggesting this therapy to be benefi cial in appropriate patients. 

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