THE INVESTIGATION OF ATHEROSCLEROTIC HEART DISEASE BY THALLIUM-201 STRESS-REINJECTION SPECT, ECHOCARDIOGRAPHY AND SERUM LIPID PROFILES IN CAPD PATIENTS

The aim of our study was to investigate coronary artery disease( CAD) in patients receiving continuous ambulatory peritoneal dialysis (CAPD) treatment. We performed thallium-201 stress-reinjection myocard perfusion SPECT, echocardiography (ECHO) and determined serum lipid profiles in 15 patients receiving CAPD treatment. Serum lipid profile abnormalities were detected in 10 patients. 'Left ventricular hypertrophy (LVH) and diastolic dysfunction (DD) were detected in 8 patients echocardiographically. Myocard perfusion abnormalities were observed in 3 of 5 patients with angina pectoris and one patient without angina pectoris. Anterolateral ischemia, anteroapical ischemia and anterior-inferior fixed perfusion defects were detected in 3 patients with angina pectoris and apical ischemia in a patient without anginal symptom. 2 of these 4 patients had lipid profile abnormalities and echocardiographically LVH, DD and wall motion abnormalities were detected in these patients.

Because the incidence of CAD is high and the etiology is multifactoriel in patients receiving CAPD, to diagnose of CAD in early period is extremely important to decrease cardiovasculary morbidity and mortality.