Turkish Journal of Nephrology
Case Report

Tacrolimus-Induced Pure Red Cell Aplasia Following Renal Transplantation: A Case Report and Literature Review

1.

Division of Nephrology, Department of Internal Medicine, Yeditepe University School of Medicine, İstanbul, Turkey

2.

Division of Hematology, Department of Internal Medicine, Yeditepe University School of Medicine, İstanbul, Turkey

3.

Department of Surgery, Yeditepe University School of Medicine, İstanbul, Turkey

Turkish J Nephrol 2021; 30: 90-92
DOI: 10.5152/turkjnephrol.2021.4316
Read: 17 Downloads: 12 Published: 04 February 2021

Anemia is common in end-stage renal disease, but it resolves rapidly after transplantation due to normalization of kidney function. Acquired pure red cell aplasia (PRCA) is an infrequent complication in kidney recipients. PRCA is a rare cause of profound anemia characterized by reticulocytopenia and marked reduction or absence of erythroid precursor. In this condition, all other cell lines are found in standard numbers and appear morphologically normal in the bone marrow. We herein report a case of a living-related kidney recipient who presented with severe anemia and developed PRCA associated with tacrolimus. The patient was successfully treated by switching tacrolimus to cyclosporine. 

Cite this article as: Barutçu Ataş D, Yavuz S, Kantarcı G, Özkan HA, Demircan F, Tellioğlu G. Tacrolimus-Induced Pure Red Cell Aplasia Following Renal Transplantation: A Case Report and Literature Review. Turk J Nephrol 2021; 30(1): 83-5.

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