Turkish Journal of Nephrology
Original Article

Risk Factors Affecting 5-Year Mortality in Incident Hemodialysis Patients in the Black Sea Region of Türkiye

1.

Dmed Samsun Dialysis Clinic, Samsun, Türkiye

2.

Department of Nephrology,Ondokuz Mayıs University, Faculty of Medicine, Samsun, Türkiye

3.

Department of Nephrology, Demiroğlu Bilim University, Faculty of Medicine, İstanbul, Türkiye

Turkish J Nephrol 2023; 32: 221-227
DOI: 10.5152/turkjnephrol.2023.2246318
Read: 553 Downloads: 263 Published: 01 July 2023

Objective: This study aimed to investigate the risk factors for all-cause mortality in incident hemodialysis patients during 5 years of the follow-up period.

Methods: The study was conducted with 163 incident hemodialysis patients in the Black Sea region of Turkey. The patients were followed up for up to 5 years. The Cox proportional hazards regression analysis was used to detect the independent risk factors that affect mortality.

Results: The median duration of follow-up was 50 (25-60) months. A total of 73 (44.8%) patients died during the 5 years of the follow-up period. The 5- year survival was 52%. Age ≥ 65 years [hazard ratio (95% CI): 1.917 (1.068-3.444); P = .029], use of a central venous catheter [hazard ratio (95% CI): 4.136 (2.338-7.319); P < .0001], serum albumin < 3.5 g/dL [hazard ratio (95% CI): 3.689 (1.876-7.257); P < .0001], corrected calcium < 8.4 mg/dL [hazard ratio (95% CI): 2.219 (1.132-4.351); P = .020], parathyroid hormone < 150 pg/mL [hazard ratio (95% CI): 2.243 (1.048-4.803); P = .037], uric acid > 7 mg/dL [hazard ratio (95% CI): 2.386 (1.154-4.933); P = .019], hemoglobin < 10 g/dL [hazard ratio (95% CI): 2.404 (1.280-4.515); P = .006], and transferrin saturation < 20% [hazard ratio (95% CI): 2.215 (1.102-4.453); P = .026] were identified as independent risk factors for mortality.

Conclusion: Advanced age, use of a central venous catheter, hypocalcemia, hypoalbuminemia, hyperuricemia, adynamic bone disease, hemoglobin < 10 g/dL, and transferrin saturation < 20% are associated with an increased all-cause mortality risk in incident hemodialysis patients.

Cite this article as: Erdem E, Karataş A, Ecder T. Risk factors affecting 5-year mortality in incident hemodialysis patients in the black sea region of Turkey. Turk J Nephrol. 2023;32(3):221-227.

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