RENAL INVOLVEMENT IN BRUCELLOSIS

BACKGROUND: Brucellosis is a zoonotic disease transmitted infected animals to humans. The kidney involvement is rare seen in brucellosis. In this study we aimed to investigate the renal involvement in brucellosis. With clinical and laboratuary data

MATERIALS and METHODS: We included the patients diagnosed brucellosis who admitted to the Van State Hospital Department of Infectious Disease and Yüzüncü yd University Training Hospital Department of Internal Medicine. Brucellosis was diagnosed by standard tube agglutination titers equal or higher than 1/160 with compatible clinical findings. Complete urine analysis, urine culture and biochemical analysis were performed.

RESULTS: The patients were between the ages 14- 65 years (mean: 33.4 ± 14.1) and half of them were male.Increase in urine urobilinogen was found in 18 patients (56.3 %), proteinuria in 16 (50 %-degrees of proteinuria were moderate in 10 patients, mild in 6 patients), bilirubiuria in 15 patients (46.9 %), microscopic hematuria in 9 patients (28.2 %) and ketonuria in 7 patients (21.9 %). In addition serum sodium levels weer detected decreased in 5 cases (15.6 %), and increase in one case (3.1 %). We did not find prominent renal failure and asit-base metabolism disorders in any patient.

CONCLUSION: Brucellosis can cause more renal involvement move than expected rates. We determined prominent proteinuria (mild or moderate), bilirubinuria, and an increase in urine urobilinogen. We rarely found deterioration in sodium metabolism.