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Objective: The most common reason for hospitalization in hemodialysis patients is related to complications due to vascular access dysfunction. Therefore, studies on maintaining arteriovenous fistula continuity for a longer period are still up-todate. The aim of this study was to determine the relationship between late arteriovenous fistula thrombosis and complete blood count parameters (especially, mean platelet volume) that were evaluated before arteriovenous fistula creation in hemodialysis patients.
Methods: Forty-six end-stage kidney disease patients who presented to our clinic between July 1, 2020 and February 2, 2022, for arteriovenous fistula creation were included as the study population. Two groups were created: those who dialyzed without complications in the first year and those who developed thrombosis within 1 year. By evaluating the examinations of the patients, the whole blood parameters of the participants with and without thrombosis on Doppler ultrasound were compared before the arteriovenous fistula was created.
Results: Mean platelet volume values were lower in the patients with late arteriovenous fistula thrombosis than in the patients with normal arteriovenous fistula functions (P = .000). Lower hemoglobin (Hgb) values were detected in the thrombosis group (P = .000). There was a marked correlation between the risk of arteriovenous fistula thrombosis and low mean platelet volume values. While a weak positive correlation was determined between white blood cell and mean platelet volume values in thrombosed arteriovenous fistula cases (0.30 < r < 0.50, P = .468), it was found that platelet count and mean platelet volume values weakly correlated negatively (−0.30 < r < −0.50, P = .013).
Conclusion: These results suggest that preoperative low mean platelet volume values can associated with higher arteriovenous fistula thrombosis risk.
Cite this article as: Azboy D, Temiztürk Z. Relationship of arteriovenous fistula thrombosis and complete blood counting parameters in hemodialysis patients with arteriovenous fistula. Turk J Nephrol. 2023;32(4):284-287.