Turkish Journal of Nephrology
Orginal Article

Long-Term Follow-up Results of Living Kidney Donors: 20 Years of Experience

1.

Department of General Surgery and Transplantation, University of Health Sciences, İzmir Bozyaka Training and Research Hospital, İzmir, Turkey

2.

Department of Nephrology, University of Health Sciences, İzmir Bozyaka Training and Research Hospital, İzmir, Turkey

Turkish J Nephrol 2019; 28: 98-102
DOI: 10.5152/turkjnephrol.2019.3304
Read: 716 Downloads: 195 Published: 22 April 2019

Objective: We aimed to retrospectively evaluate the follow-up results of living kidney donors (LKD) at our center since 1997.

Materials and Methods: LKD instances between 1997 and 2016 were evaluated. Followed-up by at least one year post-donation were included. The criterion for progression in renal failure (RF) was more than 25% reduction in the glomerular filtration rate (GFR). The cases were divided into two groups: Group 1 (GFR<60 mL/min/1.73 m²) and Group 2 (GFR≥60 mL/min/1.73 m²) according to the GFR values obtained at the last follow-up.

Results: In this study, 205 cases were included. The mean follow-up period was 57±46 (12–215) months. The prevalence of hypertension (all of them were stage 1) and diabetes (83.3% of them were new diagnosis with no end-organ damage) before and after donation was 3.1 and 2.9% vs. 13.3 and 17.5%, respectively (p<0.05). Progressive decline in RF was observed in 29 cases (14%). None of the donors progressed to end-stage renal disease (ESRD). When compared with Group 2, Group 1 patients were older, more frequently hypertensive, and had lower GFR and higher serum uric acid levels.

Conclusion: Despite the loss of GFR due to nephrectomy, the progression to RF is rare in LKD. Baseline GFR, uric acid, and age are associated with RF progression. There is a need for a “national donor follow-up program” in Turkey.

Cite this article as: Aykas A, Tatar E. Long-Term Follow-up Results of Living Kidney Donors: 20 Years of Experience. Turk J Nephrol 2019; 28(2): 98-102.

Files
EISSN 2667-4440
3