There are many factors (hypertension, anemia, hyperparathyroidism, AV fistula, hyperhydration electrolyte imbalance, uremic toxins) which affect the cardiac functions of hemodialysis patients. In this study 11 patients who received renal transplantation were evaluated echocardiographycally and results were compared with the echocardiographic findings of 11 healthy subjects. The age of patients ranged from 24 to 62 years (mean age was 39.6 ± 3.9 years), renal graft survival was 27.7 ± 4.0 months (1222 to 49 months). Before and after the transplantation the left ventricle end systolic diameter was measured echocardiographycally as 32.1129.8 mm. respectively (p>0.05), end diastolic diameter was measured as 48.0147.4 mm. respectively (p>0.05), ejection fraction was 64.18 % I 65.27 % respectively (p>0.05). These values were significantly lower than the control values (p<0.05). As a result, myocardium of hemodialysis patients is subjected to important anatomical changes and renal transplantation does not totally correct this situation.