Caring for kidney transplant recipients (KTRs) requires specialized knowledge in areas as varied as nephrology, immunology, pharmacology, endocrinology, infectious disease, and cardiology. In this context of increasing complexity coupled with an exponential growth in medical literature, clinical practice guidelines (CPGs) aim at helping clini- cians and other caregivers to deliver evidence-based medicine and thereby, to improve patient outcomes. Furthermore, guidelines also help to expose gaps in our knowledge, and thereby suggest areas where additional research is needed.