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Hypertension (HT) continues to be one of the major causes of cardiovascular morbidity and mortality in end stage renal disease (ESRD) patients. It is assumed that blood pressure (BP) should, theoretically, be better-controlled in continuous ambulatory peritoneal dialysis (CAPD) patients compared to hemodialysis (HD) patients. However, data in literature about BP control in CAPD and HD patients is controversial
In this study, we investigated the adequacy of BP control in groups of HD and CAPD patients matched for age, sex, and primary cause of end stage renal disease. Blood pressure measurements were performed by ambulatory blood pressure monitoring (ABPM) device for 48-hours in HD patients and for 24-hours in CAPD patients.
Twenty five HD patients (12 female, 13 male; mean age 47.1 ± 14.8 years; mean duration of dialysis, 39.1 ± 51.4 months), and 25 CAPD patients (12 female, 13 male; mean age 46.7 ± 14.1 years; mean duration of dialysis 27.5 ± 16.1 months) were included in the study. Twelve (%48) patients in HD group and 16 (%64) patients in CAPD group were on antihypertensive treatment (p=0.51). Mean 24-hour, day time and night time systolic (SBP) diastolic (DBP) blood pressures were significantly higher in CAPD patients compared to HD patients. Proportion of patients with uncontrolled DBP (24-h DBP >85 mm Hg) was higher in CAPD patients than HD patients (72% vs 32%, p=0.01).
In conclusion, our results demonstrate that although the number of antihypertensive drugs used to control BP were similar in HD and CAPD patients, BP is better controlled in HD patients compared to that of CAPD patients.