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Background: The goal of the present study was to compare the efect of clonazepam tablets with Noma syrup (lettuce leaf extract) on the insomnia severity in hemodialysis patients.
Methods: This randomized controlled clinical trial study was carried out with 95 eligible patients that were included in 2 groups: intervention (n = 46) and control (n = 49). Noma syrup (20 mL) was prescribed to the intervention group half an hour before going to sleep every night, and 0.5 mg of clonazepam tablets was also given to the control group half an hour before going to bed for 2 weeks. The insomnia severity index (ISI) was completed by both groups before and 2 weeks afer the intervention.
Results: The insomnia severity in the noma syrup and control groups before the intervention was 8 ± 1.77 and .20.81 ± 1.86, respectively (P = .009). But the postintervention insomnia severity in the Noma and clonazepam groups was 17.45 ± 4.13 and 16.46 ± 3.01, which was not signifcant (P = .184). The analysis of the preintervention insomnia severity index did not reveal a signifcant relationship among the studied groups in relation to the postintervention sleep scores.
Conclusion: According to the results, Noma syrup and clonazepam tablets were equally eficient in treating the insomnia of hemodialysis patients.
Cite this article as: Azad Farzin A, Bagheri-Nesami M, Setareh J, Moosazadeh M, Espahbodi F, Jokar A. Comparing the efect of clonazepam tablets with that of Noma syrup (lettuce leaf extract) on the severity of insomnia in hemodialysis patients. Turk J Nephrol. 2024;33(2):210-216.