Turkish Journal of Nephrology
Case Report

An Unusual Case of Acute Kidney Injury with AA Amyloidosis

1.

Department of Nephrology, Ankara University School of Medicine, Ankara, Turkey

2.

Department of Pathology, Ankara University School of Medicine, Ankara, Turkey

Turkish J Nephrol 2020; 29: 247-249
DOI: 10.5152/turkjnephrol.2020.4061
Read: 297 Downloads: 129 Published: 23 June 2020

Acute kidney injury (AKI) is an initial clinical diagnosis in patients with rapid renal function deterioration. Underlying etiologies of AKI include primary kidney diseases, such as acute glomerular and vasculitic diseases, tubulointerstitial nephritis (TIN); systemic insults, such as ischemia and toxins; and obstructive nephropathy. Acute TIN is a common cause of AKI and may be caused by systemic autoimmune conditions, such as immunoglobulin G4-related diseases (IgG4-RD). To date, only one case demonstrates the association of IgG4-RD and AA amyloidosis. Here we report an IgG4-related TIN (IgG4-TIN) and AA amyloidosis in a patient who presented with gross hematuria, proteinuria, and AKI. IgG4-TIN should be considered as a potential cause of AKI as well as chronic kidney disease regarding its long-term inflammatory effects on the kidney.

Cite this article as: Eren Sadioğlu R, Kiremitçi S, Kutlay S, Şengül Ş. An Unusual Case of Acute Kidney Injury with AA Amyloidosis. Turk J Nephrol 2020; 29(3): 247-9.

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