The Positive Culture Ratio and Outcome of CAPD Patients With Peritonitis

Peritonitis that is the most common and important complication of CAPD cause morbidity and mortality. Early diagnosis and early isolation, identification and determination of antibiotic sensitivity of the causative microorganism for treatment of CAPD peritonitis are very important for solving the problem. Isolation of the causative microorganism was investigated by culture methods in the patients with peritonitis during CAPD treatment in our center.

115 CAPD patients (mean age 48.0±12.5 year, 60 female, 55 male) who were followed in our center were investigated. Throughout this period, the cultures (BACTEC aerob, EMB and bloody agar) of dialysis fluid connected with 71 peritonitis episodes were made in the 40 patients with peritonitis and exit site and tunnel infections were evaluated prospectively. There was positive culture in 40 of 71 samples (%56). Microorganism was seen in 22 of 40 samples with positive culture by gram stain of the spun deposit. Coagulase negative staphylococcuss was the most frequently observed microorganism. We found gram negative microorganism in 10 patients (%25), mycobacteria in 2 patients and candida in one patient. We did not find any causative microorganism in 44% cases. 93% of cases improved completely with medical treatment. Peritoneal catheter was removed only in 2 patients with tunnel infection and 3 patients with tbc and fungal peritonitis. One patient died due to sepsis. There was exit site infection in the 25 peritonitis episode (%35).

In conclusion, the positive culture ratio was found 56% in our center. Exit site infection accompanied approximately one third of peritonitis episodes. While 93% of cases improved, one patient died.