Turkish Journal of Nephrology
Original Article

The Effect of a Single Hemodialysis Session on Pulmonary Functions in Patients with End-Stage Renal Disease

1.

Department of Pulmonology, Recep Tayyip Erdoğan Univesity School of Medicine, Rize, Turkey

2.

Department of Nephrology, Recep Tayyip Erdoğan Univesity School of Medicine, Rize, Turkey

3.

Atatürk Chest Surgery and Chest Disease Training and Research Hospital, Ankara, Turkey

Turkish J Nephrol 2021; 30: 279-286
DOI: 10.5152/turkjnephrol.2021.21938
Read: 231 Downloads: 65 Published: 13 October 2021

Objective: Changes in pulmonary functions have not been thoroughly investigated in patients undergoing hemodialysis (HD). The aim of this study was to determine the effect of a single HD session on pulmonary functions, measured by spirometry, in patients with end-stage renal disease (ESRD) undergoing chronic hemodialysis (CHD) treatment.
Methods: Thirty patients with ESRD who were on CHD treatment for at least 12 months between January 2018 and January 2020 were enrolled. The pre-dialysis and post-dialysis spirometric measurements were recorded by a portable spirometry device.
Results: The mean age and HD vintage of 30 patients (70% male, 20% diabetic, mean BMI: 26.0 ± 4.7 (kg/m2)) were 55.6 ± 11.4 years and 117.6 ± 66.3 months, respectively. Half of the patients (50%) were smokers (mean 11.5 ± 13.59 packs/year). The spirometric measurements of most of the patients were abnormal (40% restrictive, 30% obstructive respiratory disorder, 30% normal). The FEV3(L), predicted FEV1(%), FEF25(L), and predicted FEF25(%) values were significantly increased after the HD session. A positive correlation between BMI and Delta FEV3 (L) values (r = 0.377, P = .04) was observed. A significant improvement in FEV3 values after a single HD session was recorded, which was independently related to higher BMI (β = 0.501, P < .01) and non-smoking (β = 0.495, P < .05).
Conclusion: Spirometric measurements are abnormal in most CHD patients, and a considerable improvement in pulmonary functions is possible with a single HD session. Having a high BMI and being a non-smoker appear to have significant positive effects on amelioration in FEV3 (L). Larger trials are needed to evaluate pulmonary functions in CHD patients.
Cite this article as: Yılmaz Kara B, Kara E, Özyurt S, et al. The effect of a single hemodialysis session on pulmonary functions in patients with end-stage renal disease. Turk J Nephrol. 2021; 30(4): 279-286.

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