The Association Between Serum Uric Acid and 25-Hydroxyvitamin D in Peritoneal Dialysis Patients

OBJECTIVE: In peritoneal dialysis (PD) patients, a low level of serum 25-hydroxyvitamin D is associated with an increased risk of cardiovascular events. Hyperuricemia is also associated with an increased mortality rate in chronic kidney disease patients. The aim of our study was to determine whether there was a relationship between serum uric acid and 25-hydroxyvitamin D in PD patients.

MATERIAL and METHODS: A total of 48 PD patients were included in the study. Uric acid and 25-hydroxyvitamin D were determined simultaneously in each patient’s serum. Mean serum uric acid and 25-hydroxyvitamin D levels of the patients were compared with each other. The cases where the P-value was below 0.05 were considered statistically significant.

RESULTS: There was a statistically significant positive correlation between mean serum uric acid and 25-hydroxyvitamin D levels in PD patients (p=0.003; r=0.427).

CONCLUSION: Serum uric acid and 25-hydroxyvitamin D levels in peritoneal dialysis patients may be indicative of dietary incompatibility. Prospective studies involving more patients are needed in PD patients to prove a relationship between these two serum markers.