Turkish Journal of Nephrology
Original Article

Relationship Between Serum Zinc Levels, Hormonal Profiles and Sexual Dysfunctions in Male Hemodialysis Patients


Dicle Üniversitesi Tıp Fakültesi, İç Hastalıkları AD, Diyarbakır


Dicle Üniversitesi Tıp Fakültesi, Nefroloji BD, Diyarbakır

Turkish J Nephrol 2006; 15: 218-222
Read: 491 Downloads: 627 Published: 14 February 2019

OBJECTIVES: To investigate the frequency of sexual disorders and the relationship between serum zinc levels, hormonal profiles and sexual dysfunctions in male HD patients.

MATERIALS and METHODS: Forty-one male patients who were on chronic HD programme for at least six months, and treated by conventional bicarbonated HD 15 hours/week were evaluated. The serum levels of PRL, FSH, LH, progesterone, testosteron, TSH, free thyroxine and zinc were measured. A personal questionnaire was used to evaluate the sexual dysfunctions.

RESULTS: Three of the 41 patients had low serum zinc levels. Thirty-three (80.5%) of patients had elevated PRL levels. 17 (41.5%) of the patients had premature ejaculation, 10 (24.4%) had erectile dysfunction, 7 (17%) had impotence, and 7(17%) had decreased libido. A positive correlation was found between age and impotence (r=0.594, p=0.000) and between hypozincemia and premature ejaculation (r=0.334, p=0.033). A negative correlation was found between HD duration and PRL levels (r=-0.363, p=0.020). There was not any significant correlation between hypozincemia and hyperprolactinemia (r=0.084, p=0.456).

CONCLUSION: Hypozincemia and hyperprolactinemia were prevalant among HD patients. No correlation was found between hypozincemia and hyperprolactinemia. PRL levels decreased due to HD duration. A correlation was found between serum Zn levels and premature ejaculation.

EISSN 2667-4440