Posterior reversible encephalopathy syndrome (PRES), is a clinical-radiological entity that is caused by various etiological factors, usually associated with vasogenic edema in the posterior parietal and occipital regions, and the magnetic resonance imaging findings are diagnostic. Although treatment of the underlying cause provides clinical and radiological healing, cases have been reported with recurrence and rarely mortality. In this article, we reviewed the literature together with a patient who had chronic kidney disease and loss of consciousness and was diagnosed as PRES after the investigations.