OXIDANT STRES AND ANTIOXIDANT DEFENCE IN HEMODIALYSIS PATIENTS

In hemodialysis patients, oxidant stress increases and antioxidant defence decreases. In spite of a lot of factors play a role in this impaired balance, hemodialysis therapy is one of the most important factors. During the hemodialysis therapy, while antioxidant enzymes is increasing, lipid peroxidation may not change. Erythropoietin therapy may effect this system.

In this review, possible reasons of increased oxidant stress and decreased antioxidant defence will be discussed.