Turkish Journal of Nephrology
Original Article
Membranoproliferative Glomerulonephritis: The Most Common Pediatric Renal Pathology at a Tertiary Center in Turkey

Membranoproliferative Glomerulonephritis: The Most Common Pediatric Renal Pathology at a Tertiary Center in Turkey

1.

Division of Pediatric Nephrology, Mersin University School of Medicine, Mersin, Turkey

2.

Department of Pathology, Mersin University School of Medicine, Mersin, Turkey

3.

Department of Radiology, Mersin University School of Medicine, Mersin, Turkey

4.

Department of Histology and Embryology, Mersin University School of Medicine, Mersin, Turkey

5.

Department of Biostatistics and Medical Informatics, Mersin University School of Medicine, Mersin, Turkey

Turkish J Nephrol 2019; 28: 263-268
DOI: 10.5152/turkjnephrol.2019.3481
Read: 1874 Downloads: 714 Published: 01 November 2019

Objective: This study aimed to assess the histopathological diagnosis of pediatric renal biopsies performed at the tertiary referral center in the city and to compare the ultrasound (USG) -guided biopsy and percutaneous renal needle biopsy (PRNB) in terms of safety.

Materials and Methods: All pediatric cases who underwent percutaneous renal biopsy at the center from January 2004 to December 2016 were reviewed retrospectively. The biopsy methods were compared in terms of complications.

Results: A total of 171 pediatric renal biopsies in 151 patients were included in the study. The most common renal pathology was primary glomerular disease (47.37%), and membranoproliferative glomerulonephritis (MPGN) was the most common glomerular pathology (19.30%). Systemic diseases (20.47%), tubulointerstitial diseases (8.77%), hereditary and congenital diseases (5.26%), chronic pyelonephritis (5.26%), and malignancy (0.58%) followed MPGN, respectively. The number of USG-guided biopsies performed by different radiologists was 79 (46.20%), and the number of PRNB performed by an experienced nephrologist was 92 (53.80%). No statistically significant difference was found between the two methods in terms of complications (p=0.50).

Conclusions: The MPGN was the most common pathology in the center. The PRNB is a safe diagnostic method for pediatric renal diseases when performed by an experienced nephrologist.

Cite this article as: Sürmeli Döven S, Delibaş A, Gürses İ, Esen K, Yuyucu Karabulut Y, Coşkun Yılmaz B, et al. Membranoproliferative Glomerulonephritis: The Most Common Pediatric Renal Pathology at a Tertiary Center in Turkey. Turk J Nephrol 2019; 28(4): 263-8.

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