Turkish Journal of Nephrology
Original Article

Levels of Plasma Homocysteine in Obese Women Subjects Homocysteine and Obesity

1.

Akdeniz University Faculty of Medicine, Department of Internal Medicine, Division of Nephrology, Antalya, Turkey

2.

Akdeniz University Faculty of Medicine, Department of Internal Medicine, Antalya, Turkey

3.

Akdeniz University Faculty of Medicine, Department of Internal Medicine, Division of Rhumatology, Antalya, Turkey

Turkish J Nephrol 2014; 23: 91-94
DOI: 10.5262/tndt.2014.1002.03
Read: 818 Downloads: 466 Published: 07 February 2019

OBJECTIVE: An increased homocysteine level is an independent risk factor for vascular diseases. The present study was designed to evaluate plasma homocysteine levels in obese women compared with non-obese healthy women.

MATERIAL and METHODS: We selected 55 obese women (mean age 47.2±9.2 years) having a body mass index ≥ 30 kg/m² and 50 non-obese healthy women matched for age (mean age 46.3±9.5 years) who attended our outpatients clinic. We measured levels of homocysteine in obese and nonobese groups.

RESULTS: No significant difference was observed between obese and non-obese control groups regarding the homocysteine levels (10.3±3.5 µmol/l vs. 10.1±3.8 µmol/l , p>0.05). In this selected study population as a whole, the correlation between homocysteine levels and body mass index did not attain statistical significance (r=0.12, p>0.05).

CONCLUSION: We found that homocysteine levels were comparable between middle-aged obese and non-obese women. Our data may suggest that increased cardiovascular risk in obese women is probably not related to the homocysteine level. 

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