Turkish Journal of Nephrology
Original Article

Is Nocturnal Systolic Blood Pressure Rise Associated with Central Hemodynamics and Arterial Stiffness?

1.

Selçuk Üniversitesi Selçuklu Tıp Fakültesi, Nefroloji Bilim Dalı, Konya, Türkiye

Turkish J Nephrol 2012; 21: 235-241
DOI: 10.5262/tndt.2012.1003.06
Read: 1092 Downloads: 1198 Published: 11 February 2019

OBJECTIVE: The aim of this study was to assess central hemodynamics and parameters of arterial stiffness of cases with nocturnal blood pressure rise.

MATERIAL and METHODS: In this retrospective study, ambulatory blood pressure monitoring of 252 hypertensive patients was performed with the Mobil-O-Graph Arteriograph.

RESULTS: 174 (%69.0) out of 252 patients were female and 78 (%31) were male and the mean age was 54.5±14.4. When Pearson’s correlation test was performed, the nocturnal systolic blood pressure (SBP) decline was associated with age (r=-0.169, p=0.008), diurnal pulse wave velocity (PWV) (r=-0.179, p=0.005), nocturnal diastolic blood pressure (DBP) decline (r=0.790, p<0.001), nocturnal central SBP (r=-0.410, p<0.001), and nocturnal augmentation index (Aix@75) (r=-0.215, p=0.001). When patients were divided into three groups as 10 % or more nocturnal SBP decline, less than 10 % nocturnal SBP decline and nocturnal SBP increase, there were statistically signifi cant differences regarding nocturnal pulse pressure (p<0.001), nocturnal DBP decline (p<0.001, nocturnal Aix@75 (p<0.001), and nocturnal peripheral resistance (p<0.001).

CONCLUSION: We believe that strict follow up of conventional risk factors causing arterial stiffness in patients with less than 10 % nocturnal BP decline or increase and also the use of chronotherapy may be useful.

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