Turkish Journal of Nephrology

Heavy Metals and Kidney


Department of Nephrology, Başkent University Faculty of Medicine, Dr. Turgut Noyan Training and Research Hospital, Adana, Türkiye


Division of Nephrology, Bahçeşehir University Faculty of Medicine, İstanbul, Türkiye


Division of Nephrology, Sütçü Imam University Faculty of Medicine, Kahramanmaraş, Türkiye

Turkish J Nephrol 2024; 33: 244-251
DOI: 10.5152/turkjnephrol.2024.22497
Read: 207 Downloads: 193 Published: 18 April 2024

Abstract: Metals with a density of more than 5 g/cm3 are heavy metals, with more than 60 in nature. In acute and chronic exposure, they can damage many organs, such as the central nervous system, kidneys, skin, lungs, and heart. The most harmful ones to the kidney are lead, mercury, cadmium, and arsenic. They cause damage by creating some disorders in intracellular metabolic processes. The main types of kidney injury are acute tubular damage, proteinuria, and chronic kidney disease. This review discusses the basic properties of lead, mercury, cadmium, and arsenic, their nephrotoxicity mechanisms, and studies about them.

Cite this article as: Onan E, Ulu S, Güngör Ö. Heavy metals and kidney. Turk J Nephrol. 2024;33(3):244-251.

EISSN 2667-4440