Turkish Journal of Nephrology
Original Articles

Health-Related Quality of Life of Patients with Chronic Kidney Disease on Maintenance Hemodialysis and Its Determinants: A Study from a Tertiary Hospital in South India


Department of Nephrology, M S Ramaiah Medical College, Rajiv Gandhi University of Health Sciences, Karnataka, India

Turkish J Nephrol 2024; 33: 279-288
DOI: 10.5152/turkjnephrol.2024.22484
Read: 80 Downloads: 62 Published: 14 May 2024

Background: The overall quality of life of patients with chronic kidney disease undergoing hemodialysis has not substantially improved over the years, despite the quality care provided by health-care providers. Due to the chronic nature of the disease, there is substantial psychosocial burden on patients and caregivers alike. This study was done to measure healthrelated quality of life (HRQOL) in our patients and to delineate the factors that influence HRQOL.

Methods: This was a single-center prospective cohort study. 191 patients were studied and followed up for up to 1 year. We used independent t test/Mann Whitney U test/ANOVA/Kruskal Wallis test to find the association between sociodemographic and clinical parameters with QOL domains.

Results: We found that patients who were actively working had better HRQOL as compared to unemployed patients (P <0.001). Patients who were older, those who had longer vintage of dialysis, diabetes, cardiovascular comorbidities, with history of noncompliance with hemodialysis, and an increased annual hospitalization rate had worse HRQOL (P < 0.001). We also found that patients who had higher phosphate levels and lower albumin levels had lower HRQOL (P < 0.001). Patients with higher HRQOL scores were detected to have lower odds of death [Odds ratio of Symptom/Problem List score= 0.96 (95% CI, 0.938-0.995)], which was statistically significant (P = .02).

Conclusion: This study gives an insight into the socioeconomic and medical factors associated with the QOL in chronic kidney disease patients on hemodialysis in Bengaluru, South India. Our study shows that there is poor HRQOL among hemodialysis patients and a significant association with morbidity and mortality.

Cite this article as: Eswarappa M, Anish LS, Prabhu PP, et al. Health-related quality of life of patients with chronic kidney disease on maintenance hemodialysis and its determinants: A study from a tertiary hospital in South India. Turk J Nephrol. 2024;33(3):279-288.

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