Turkish Journal of Nephrology
Original Article

Determinants of Mortality Among Elderly Subjects with Chronic Kidney Disease

1.

Division of Nephrology, Muş State Hospital, Muş, Turkey

2.

Division of Geriatrics, Bezmialem Vakıf University School of Medicine, Istanbul, Turkey

3.

Division of Nephrology, Bezmialem Vakıf University School of Medicine, Istanbul, Turkey

Turkish J Nephrol 2021; 30: 193-198
DOI: 10.5152/turkjnephrol.2021.4657
Read: 334 Downloads: 208 Published: 16 July 2021

Objective: Studies on predictors of mortality among elderly chronic kidney disease (CKD) patients have conflicting results. We aimed to assess the factors related to mortality in CKD versus non-CKD elderly subjects. 

Methods: Medical records of consecutive elderly subjects presented to geriatrics outpatient clinics were retrospectively searched. Logistic regression models were set in order to determine independent predictors of mortality. 

Results: The median age was 73 (67-80) years, and 837 (67.9%) were female. CKD constituted 21.9% of the cohort. During the follow-up of 3 to 4 years, 7.2% of the patients died. In the CKD cohort, older age (per year, OR 1.12, 95% CI 1.01-1.25, P = .040) and serum uric acid levels (per 1 mg/dL increase, OR 1.74, 95% CI 1.12-2.69, P = .013) were associated with a higher risk of mortality while serum albumin (per 1 g/dL increase, OR 0.08, 95% CI 0.01-0.52, P = .008) and vitamin D levels (per 1 ng/mL increase, OR 0.77, 95% CI 0.62-0.96, P = .019) were associated with a lower risk of mortality in the multivariate regression model.

Conclusion: Older age, lower serum albumin and vitamin D levels, and higher serum uric acid levels are independent predictors of mortality in outpatient elderly subjects with CKD.

Cite this article as: Heybeli C, Soysal P, Kazancıoğlu R. Determinants of mortality among elderly subjects with chronic kidney disease. Turk J Nephrol. 2021; 30(3): 193-198.

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