Turkish Journal of Nephrology
Original Article

COVID-19 Infection in Peritoneal Dialysis Patients: A Comparative Outcome Study with Patients on Hemodialysis and Patients without Kidney Disease

1.

Division of Nephrology, Department of Internal Medicine, Bezmialem Vakif University School of Medicine, Istanbul, Turkey

2.

Department of Nephrology, Haseki Training and Research Hospital, İstanbul, Turkey

3.

Division of Nephrology, Department of Internal Medicine, Mersin University Training and Research Hospital School of Medicine, Mersin, Turkey

4.

Department of Nephrology, Hacettepe University School of Medicine, Ankara, Turkey

5.

Department of Nephrology, Bursa Uludag University School of Medicine, Bursa, Turkey

6.

Department of Nephrology, University of Health Sciences, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey

7.

Department of Nephrology, Kocaeli University School of Medicine, Kocaeli, Turkey

8.

Department of Nephrology, University of Health Sciences, Kocaeli Derince Training and Research Hospital, Kocaeli, Turkey

9.

Department of Nephrology, University of Health Sciences, Haydarpasa Numune Training and Research Hospital, Istanbul, Turkey

10.

Department of Nephrology, Faculty of Medicine, Mugla Sıtkı Koçman University, Mugla, Turkey

11.

Department of Nephrology, Health Sciences University, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Turkey

12.

Department of Nephrology, Bursa City Hospital, Bursa, Turkey

13.

Department of Nephrology, Adana City Training and Research Hospital, Adana, Turkey

14.

Department of Nephrology, Haseki Training and Research Hospital, Istanbul, Turkey

15.

Department of Internal Medicine, Division of Nephrology, Marmara University School of Medicine, Istanbul, Turkey

16.

Division of Nephrology, Department of Internal Medicine, Istanbul University School of Medicine, Istanbul, Turkey

17.

Division of Nephrology, Department of Internal Medicine, Istanbul University–Cerrahpasa School of Medicine, Istanbul, Turkey

18.

Department of Nephrology, Erciyes University School of Medicine, Kayseri, Turkey

19.

Department of Nephrology, University of Health Sciences, Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey

20.

Department of Nephrology, Necmettin Erbakan University Meram School of Medicine, Konya, Turkey

21.

Division of Nephrology, Department of Internal Medicine, Atilim University School of Medicine, Ankara, Turkey

22.

Division of Nephrology, Department of Internal Medicine, Ankara University School of Medicine, Ankara, Turkey

Turkish J Nephrol 2022; 31: 33-42
DOI: 10.5152/turkjnephrol.2021.21045
Read: 682 Downloads: 229 Published: 12 November 2021

Objectives: There is limited data about coronavirus disease-19 (COVID-19) characteristics and results in peritoneal dialysis (PD) patients. This study aimed to investigate the characteristics and outcomes among PD patients and compare them with matched hemodialysis (HD) patients and a control group without kidney disease.

Methods: We included 18 PD patients and consecutive age- and gender-matched 18 HD and 18 patients without kidney disease (control group) registered into the Turkish Society of Nephrology database including 1301 COVID-19 patients. We compared demographic, clinical, radiological, laboratory data, and outcomes namely intensive care unit (ICU) admission, mechanical ventilation, mortality, and composite outcome (death and/or ICU admission).

Results: ICU admission, mechanical ventilation, and mortality rates in PD patients (27.8%, 22.2%, and 22.2%, respectively) and the HD group (16.7%, 11.1%, and 16.7%, respectively) were higher than the control group (11.1%, 11.1%, and 5.6%, respectively), but intergroup comparison did not reveal difference. A total of 11 (20.3%) patients had composite outcome (6 PD patients, 3 HD patients, and 2 patients in the control group). In Cox regression analysis, higher age and higher CRP level were related to increased risk of composite outcome. Adjusted rate of composite outcome in PD group was significantly higher than the control group (P = .050). This rate was similar in HD and control groups (P = .30).

Conclusions: Combined in-hospital mortality and/or ICU admission of PD patients with COVID-19 was significantly higher than the control patients. There is a need for careful surveillance of PD patients for infection signs and prompt treatment of COVID-19.

Cite this article as: Kazancıoğlu R, Öztürk Ş, Turgutalp K, et al. COVID-19 infection in peritoneal dialysis patients: A comparative outcome study with patients on hemodialysis and patients without kidney disease. Turk J Nephrol. 2022;31(1):33-42.

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