Scleroderma is a systemic autoimmune disease of unknown origin characterized by excessive deposition of collagen and other connective tissue macromolecules in multiple organs. It can cause thrombotic microangiopathy. Scleroderma renal crisis is a major complication of this disorder. We aimed to present a case that presented with thrombotic microangiopathy findings and was diagnosed as scleroderma renal crisis.
A 56-year-old female patient presented with hypertension and thrombotic microangiopathy signs. After examination and renal biopsy, scleroderma renal crisis with thrombotic microangiopathy was diagnosed. A routine hemodialysis program and an angiotensin converting enzyme inhibitor was started Scleroderma renal crisis should be kept in mind in patients presenting with malignant hypertension and thrombotic microangiopathy.