Turkish Journal of Nephrology
Case Report

Case Report: Scleroderma Renal Crisis Presenting as Thrombotic Microangiopathy

1.

İzmir Tepecik Education and Research Hospital, Department of Internal Medicine, İzmir, Turkey

2.

İzmir Tepecik Education and Research Hospital, Department of Pathology, İzmir, Turkey

3.

İzmir Tepecik Education and Research Hospital, Department of Nephrology, İzmir, Turkey

4.

İzmir Tepecik Education and Research Hospital, Department of Hematology, İzmir, Turkey

Turkish J Nephrol 2016; -1: Supplement 71-74
DOI: 10.5262/tndt.2016.12
Read: 1399 Downloads: 883 Published: 01 February 2019

Scleroderma is a systemic autoimmune disease of unknown origin characterized by excessive deposition of collagen and other connective tissue macromolecules in multiple organs. It can cause thrombotic microangiopathy. Scleroderma renal crisis is a major complication of this disorder. We aimed to present a case that presented with thrombotic microangiopathy findings and was diagnosed as scleroderma renal crisis.

A 56-year-old female patient presented with hypertension and thrombotic microangiopathy signs. After examination and renal biopsy, scleroderma renal crisis with thrombotic microangiopathy was diagnosed. A routine hemodialysis program and an angiotensin converting enzyme inhibitor was started Scleroderma renal crisis should be kept in mind in patients presenting with malignant hypertension and thrombotic microangiopathy. 

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