Turkish Journal of Nephrology
Case Report

Bilateral Renal Infarction due to MTHFR C677T Mutation and Hyperhomocysteinemia

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Kahramanmaraş Sütçü İmam Üniversitesi, Tıp Fakültesi, Nefroloji Bilim Dalı, Kahramanmaraş, Türkiye

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Kahramanmaraş Sütçü İmam Üniversitesi, Tıp Fakültesi, Hematoloji Anabilim Dalı, Kahramanmaraş, Türkiye

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Kahramanmaraş Sütçü İmam Üniversitesi, Tıp Fakültesi, Radyoloji Anabilim Dalı, Kahramanmaraş, Türkiye

Turkish J Nephrol 2018; 27: 327-330
DOI: 10.5262/tndt.2018.2971
Read: 1392 Downloads: 747 Published: 30 January 2019

Renal infarction is a condition induced by renal artery occlusion and causes renal parenchymal damage. The most common cause of renal infarction is atheroembolic cardiac diseases. Other causes are trauma, autoimmune diseases and hypercoagulability. Homocysteine is a vasculotoxic substance, and mutations in the Methyltetrahyrofolate Reductase (MTHFR) enzyme may result in an increase in serum homocysteine levels. In this report, we present a 35-year-old case with bilateral renal infarction, for which we hold the MTHFR C677T mutation and hyperhomocysteinemia responsible, because of its rarity.

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