Tuberculosis (Tbc) continues to threaten humanity. Amyloidosis is one of the most common complication of Tbc. Proteinuria can be observed during the clinical follow-up and it may mimic nephrotic syndrome. In this case report, a 45-year-old man who was diagnosed with cavitary Tbc detected during the search for the etiology of the proteinuria was presented. The symptoms regressed with anti-tbc therapy.