Solid organ transplant patients have higher suicide rates compared to the general population. It is suggested that the major factor contributing to this is to be on multiple immunosupressive drugs, with some of these drugs directly or as a side effect potentially affecting the neurophysiatric system. Mycophenolate sodium (MPS) is an immunosupressive drug used in transplantation and is considered as a relatively safe, non-nephrotoxic agent with relatively few side effects. Common side effects are related to gastrointestinal (nausea, vomiting and diarrhea) and haemopoietic system (neutropenia and mild anemia). However, data on drug overdose and toxicity is limited. In this paper, we report successful management and outcome of renal transplant patient who had committed suicide by ingesting MPS.